Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of endothelial barrier function during flow-induced conversion to an arterial phenotype.

Cardiovascular research - 1 Aug 2007

Seebach Jochen, Donnert Gerald, Kronstein Romy, Werth Sebastian, Wojciak-Stothard Beata, Falzarano Darryl, Mrowietz Christof, Hell Stefan W, Schnittler Hans-J

Abstract excerpt

OBJECTIVE: Flow-induced conversion of endothelial cells into an elongated arterial phenotype requires a coordinated regulation of cell junctions. Here we investigated the effect of acute and chronic flow on junction regulation. METHODS AND RESULTS: Using an extended experimental setup that allows analyses of endothelial barrier function under flow conditions, we found a flow-induced upregulation of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arteries
Share to Cell Membrane Permeability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intercellular Junctions

Share to rac1 GTP-Binding Protein

Share to Regional Blood Flow

Share to rho GTP-Binding Proteins

Share to Stress, Mechanical

Source

Identifiers

PMID: 17531214
DOI: 10.1016/j.cardiores.2007.04.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of endothelial barrier function during flow-induced conversion to an arterial phenotype.PMID 17531214Read ↗

Flow-mediated signaling modulates endothelial cell phenotype.Semantic proximity Read ↗

Endothelial mechanobiology under controlled disturbed flowsSemantic proximity Read ↗

Early events in endothelial flow sensingSemantic proximity Read ↗

Adaptive phenotypic modulation of human arterial endothelial cells to fluid shear stress-encoded signals: modulation by phosphodiesterase 4D-VE-cadherin signalling.Semantic proximity Read ↗

Biomechanical activation of vascular endothelium as a determinant of its functional phenotype.Semantic proximity Read ↗

Shear Difference: Flow Type Dictates Endothelial Flow-Responsive Gene Programs in a 3D-Printed in vitro ModelSemantic proximity Read ↗

Interstitial Fluid Shear Stress Induces the Synthetic Phenotype Switching of VSMCs to Release Pro-calcified Extracellular Vesicles via EGFR-MAPK-KLF5 Pathway.Semantic proximity Read ↗

In vivo modulation of endothelial polarization by Apelin receptor signallingSemantic proximity Read ↗

Neutrophil motility is regulated by both cell intrinsic and endothelial cell ARPC1BSemantic proximity Read ↗

Latrophilin-2 mediates fluid shear stress mechanotransduction at endothelial junctionsSemantic proximity Read ↗

Thioredoxin-Interacting Protein Is a Biomechanical Regulator of Src ActivitySemantic proximity Read ↗

TRPV4 channel activation induces the transition of venous and arterial endothelial cells toward a pro-inflammatory phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.