Article

Quantitative assessment of association between noncoding variants and transcription factor binding

2022-11-23

Abstract excerpt

Association fine-mapping of molecular traits is an essential method for understanding the impact of genetic variation. Sequencing-based assays, including RNA-seq, DNase-seq and ChIP-seq, have been widely used to measure different cellular traits and enabled genome-wide mapping of quantitative trait loci (QTLs). The disruption of cis-regulatory sequence, often occurring through variation within transcription factor...

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Literature Corpus work: c77f4de1-f1f4-59cd-8ae5-ef4910c3f9cb
DOI: 10.1101/2022.11.22.517559

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