Article

DNA-binding factor footprints and enhancer RNAs identify functional non-coding genetic variants

2023-11-20

Abstract excerpt

Genome-wide association studies (GWAS) have revealed a multitude of candidate genetic variants affecting the risk of developing complex traits and diseases. However, these highlighted regions are typically in the non-coding genome, and uncovering the functional causative single nucleotide variants (SNVs) is challenging. Prioritisation of variants is commonly based on functional genomic annotation with markers of a...

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Literature Corpus work: f3481eb8-ad68-5f56-bd8a-7fe48c847afa
DOI: 10.1101/2023.11.20.567860

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