Article

Investigating genetic determinants of ankylosing spondylitis

2003-01-01

Abstract excerpt

Ankylosing spondylitis (AS) is a common form of inflammatory arthritis, occurring in approximately 0.1% of the British and Finnish populations. The genetic contribution to the disease susceptibility accounts for >90% of the population variance, and the disease severity is also predominantly genetically determined. HLA-B27 has been strongly associated with the disease world-wide, but although it is almost essential...

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Literature Corpus work: c76a5d93-3767-5c60-bd9d-72f208b2ffeb
DOI: 10.21954/ou.ro.0000e81c

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