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Article

Ankylosing spondylitis: beyond genome-wide association studies.

Current opinion in rheumatology - 1 Jul 2016

O'Rielly Darren D, Uddin Mohammed, Rahman Proton

Abstract excerpt

PURPOSE OF REVIEW: This article discusses genomic investigations in ankylosing spondylitis (AS) beyond genome-wide association (GWA) studies, but prior to this, genetic variants achieving genome-wide significance will be summarized highlighting key pathways contributing to disease pathogenesis. RECENT FINDINGS: Evidence suggests that disease pathogenesis is attributed to a complex interplay of genetic,...

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Identifiers

PMID: 27224740
DOI: 10.1097/BOR.0000000000000297

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