Article
Allele frequency spectrum of known ankylosing spondylitis associated variants in a Swedish population.
Scandinavian journal of rheumatology - 1 Jan 2022
Mathioudaki A, Nordin J, Kastbom A, Söderkvist P, Eriksson P, Cedergren J, Lindblad-Toh K, Meadows Jrs
Abstract excerpt
Objective: The genetic predisposition to ankylosing spondylitis (AS) has been most widely studied in cohorts with European ancestry. However, within Europe, disease prevalence is higher in Sweden. Given this, we aimed to characterize known AS susceptibility variants in a homogeneous Swedish data set, assessing reproducibility and direction of effect.Method: The power to detect association within an existing...
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