Article
The effect of transforming growth factor beta1 gene polymorphisms in ankylosing spondylitis.
Rheumatology (Oxford, England) - 1 Jan 2004
Jaakkola E, Crane A M, Laiho K, Herzberg I, Sims A-M, Bradbury L, Calin A, Brophy S, Kauppi M, Kaarela K, Wordsworth B P, Tuomilehto J, Brown M A
Abstract excerpt
OBJECTIVES: To determine whether genetic polymorphisms in or near the transforming growth factor beta1 (TGFB1) locus were associated with susceptibility to or severity of ankylosing spondylitis (AS). METHODS: Five intragenic single-nucleotide polymorphisms (SNP) and three microsatellite markers f...
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