Article
Genetics of ankylosing spondylitis--insights into pathogenesis.
Nature reviews. Rheumatology - 1 Feb 2016
Brown Matthew A, Kenna Tony, Wordsworth B Paul
Abstract excerpt
Ankylosing spondylitis (AS), an immune-mediated arthritis, is the prototypic member of a group of conditions known as spondyloarthropathies that also includes reactive arthritis, psoriatic arthritis and enteropathic arthritis. Patients with these conditions share a clinical predisposition for spinal and pelvic joint dysfunction, as well as genetic associations, notably with HLA-B(*)27. Spondyloarthropathies are...
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