Article
HLA-B27 and genetic predisposing factors in spondyloarthropathies.
Current opinion in rheumatology - 1 Jul 2001
Reveille J D, Ball E J, Khan M A
Abstract excerpt
With the mapping of the human genome having been completed, our ability to investigate and ideally better understand the genetic basis of rheumatic diseases is advancing at a rapid pace. Substantial evidence strongly favors a direct role for HLA-B27 in genetic susceptibility to ankylosing spondylitis and related spondyloarthropathies, although the underlying molecular basis has yet to be identified. HLA-B27...
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