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A Fractal-Dimension Framework for Quantifying Self-Similarity in Chromatin Folding

2026-05-09

Abstract excerpt

The three-dimensional folding of DNA is essential for genome function, but its organization remains difficult to summarize quantitatively across genomic scales. Here, we study DNA folding from Hi-C contact data using a network-based notion of fractal dimension. In this representation, genomic loci are treated as nodes, and observed Hi-C contacts define weighted edges, so that frequently interacting loci are closer...

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Literature Corpus work
c7486633-3d88-5bde-a622-c5be9e13aa95
DOI
10.64898/2026.05.06.723123
Open publication

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A Fractal-Dimension Framework for Quantifying Self-Similarity in Chromatin FoldingDOI 10.64898/2026.05.06.723123
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