Article

Mustache: Multi-scale Detection of Chromatin Loops from Hi-C and Micro-C Maps using Scale-Space Representation

2020-02-26

Abstract excerpt

We present M ustache , a new method for multi-scale detection of chromatin loops from Hi-C and Micro-C contact maps. M ustache employs scale-space theory, a technical advance in computer vision, to detect blob-shaped objects in a multi-scale representation of chromatin contact maps parametrized by the size of the smoothing kernel. When applied to high-resolution Hi-C and Micro-C data, M ustache detects loops at...

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Literature Corpus work: 1e972c9f-15ee-58fd-88c0-59afd097abf8
DOI: 10.1101/2020.02.24.963579

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