Article

dcHiC: differential compartment analysis of Hi-C datasets

2021-02-02

Abstract excerpt

The compartmental organization of chromatin and its changes play important roles in distinct biological processes carried out by mammalian genomes. However, differential compartment analyses have been mostly limited to pairwise comparisons and with a main focus on only the compartment flips (e.g., A-to-B). Here, we introduce dcHiC , which utilizes quantile normalized compartment scores and a multivariate distance...

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Literature Corpus work: 1f602b7c-4f14-5213-91e4-c05b418659a0
DOI: 10.1101/2021.02.02.429297

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