Article

Comprehensive analysis of mutations and clonal evolution patterns in a cohort of patients with cytogenetically normal acute myeloid leukemia

2021-04-27

Abstract excerpt

<title>Abstract</title> <p>Background Relapsed acute myeloid leukemia (AML) is associated with the acquisition of additional somatic mutations which are thought to drive phenotypic adaptability driving clonal selection during treatment and evolution of leukemic clones. We performed high throughput exome sequencing of matched presentation and relapsed samples from 6 cytogenetically normal AML (CN-AML) patients tr...

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Literature Corpus work: c7094835-bcc6-53c7-b3e1-4fa1bb77bc26
DOI: 10.21203/rs.3.rs-456155/v1

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