Article

Clonal Evolution of Acute Myeloid Leukemia Revealed by High-Throughput Single-Cell Genomics

2020-02-07

Abstract excerpt

<h4>Summary</h4> One of the pervasive features of cancer is the diversity of mutations found in malignant cells within the same tumor; a phenomenon called clonal diversity or intratumor heterogeneity. Clonal diversity allows tumors to adapt to the selective pressure of treatment and likely contributes to the development of treatment resistance and cancer recurrence. Thus, the ability to precisely delineate the cl...

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Literature Corpus work: 47381f40-83e9-585e-ae0e-9c60fe813043
DOI: 10.1101/2020.02.07.925743

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