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Article

Clonal Evolution in 207 Cases of Refractory or Relapsed Acute Myeloid Leukemia.

European journal of haematology - 1 Jan 2025

Murray Graeme F, Bouligny Ian M, Ho Thuy, Gor Juhi, Zacholski Kyle, Wages Nolan A, Grant Steven, Maher Keri R

Abstract excerpt

Clonal evolution (CE) is a driving force behind the development and progression of acute myeloid leukemia (AML). Advances in molecular and cytogenetic assays have improved the depth and breadth of detection of CE in AML, which is defined here as a detected change in cytogenetic or molecular profile at relapsed or refractory (RR) disease. In this study, we demonstrate the clinical impact of CE in a cohort of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39315590
DOI: 10.1111/ejh.14308
PMCID: PMC11614692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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