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Comprehensive insights into AML relapse: genetic mutations, clonal evolution, and clinical outcomes

19 May 2024

Abstract excerpt

INTRODUCTION: Acute myeloid leukemia (AML) is a complex hematologic malignancy characterized by uncontrolled proliferation of myeloid precursor cells within bone marrow. Despite advances in understanding of its molecular underpinnings, AML remains a therapeutic challenge due to its high relapse rate and clonal evolution. METHODS: In this retrospective study, we analyzed data from 24 AML patients diagnosed at a...

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PMID: 38764048
DOI: 10.1186/s12935-024-03368-4

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