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Article

New molecular abnormalities and clonal architecture in AML: from reciprocal translocations to whole-genome sequencing.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting - 1 Jan 2014

Graubert Timothy A, Brunner Andrew M, Fathi Amir T

Abstract excerpt

Acute myeloid leukemia (AML) is characterized by recurrent genetic alterations, including amplifications, deletions, rearrangements, and point mutations. Clinically, these lesions can be used to stratify patients into categories of risk, which directs further clinical management and prognostication. Patient risk categories were first described based on recurrent karyotypic abnormalities; most patients with AML,...

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Source

Identifiers

PMID: 24857122
DOI: 10.14694/EdBook_AM.2014.34.e334

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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