Article

Systematic mapping of rRNA 2’-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in <i>Xenopus laevis</i>

2021-11-25

Abstract excerpt

<h4>ABSTRACT</h4> Ribosomes are essential nanomachines responsible for protein production. Although ribosomes are present in every living cell, ribosome biogenesis dysfunction diseases, called ribosomopathies, impact particular tissues specifically. Here, we evaluate the importance of the box C/D snoRNA-associated ribosomal RNA methyltransferase fibrillarin (Fbl) in the early embryonic development of Xenopus lae...

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Literature Corpus work: c6eb406a-bafa-50e9-acb4-20a770bb0a69
DOI: 10.1101/2021.11.25.469989

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