Article

Nucleolin loss-of-function leads to aberrant FGF signaling and craniofacial anomalies

2021-09-15

Abstract excerpt

rRNA transcription and ribosome biogenesis are global processes required for growth and proliferation of all cells, yet perturbation of these processes in vertebrates leads to tissue-specific defects termed ribosomopathies. Mutations in rRNA transcription and processing proteins often lead to craniofacial anomalies, however the cellular and molecular reasons for this are poorly understood. Therefore, we examined t...

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Literature Corpus work: d6acc95d-b9fd-59bb-8c28-568809c718e7
DOI: 10.1101/2021.09.14.460382

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