Article

H3K36 Methylation - a Guardian of Epigenome Integrity

2024-08-10

Abstract excerpt

H3K36 methylation is emerging as a key epigenetic modification with strong implications in genetic disease and cancer. However, the mechanisms through which H3K36me impacts the epigenome and asserts its functional consequences are far from understood. Here, we use mouse mesenchymal stem cell lines with successive knockouts of the H3K36 methyltransferases: NSD1, NSD2, SETD2, NSD3, and ASH1L, which result in progres...

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Literature Corpus work: c66ede7c-7c48-5783-a675-5903546b5f33
DOI: 10.1101/2024.08.10.607446

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