Article

Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data

2019-03-18

Abstract excerpt

Promoter-anchored chromatin interactions (PAIs) play a pivotal role in transcriptional regulation. Current high-throughput technologies for detecting PAIs, such as promoter capture Hi-C, are not scalable to large cohorts. Here, we present an analytical approach that uses summary-level data from cohort-based DNA methylation (DNAm) quantitative trait locus (mQTL) studies to predict PAIs. Using mQTL data from human p...

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Literature Corpus work: c60fa4dc-5f10-543c-8e23-11a720d02623
DOI: 10.1101/580993

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