Article

Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

2020-09-03

Abstract excerpt

Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to understand mechanisms underpinning gene regulation and disease. Here we describe results of DNA methylation-quantitative trait loci (mQTL) analyses on 32,851 participants, identifying genetic variants associated with DNAm at 420,509 DNAm sites in blood. We present a database of >270,000 independent mQTL of which 8.5% comprise lo...

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Literature Corpus work: 7e84bc93-a98c-59fc-a8ef-04918c0616c9
DOI: 10.1101/2020.09.01.20180406

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