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Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits

2018-04-07

Abstract excerpt

<h4>ABSTRACT</h4> Characterizing the complex relationship between genetic, epigenetic and transcriptomic variation has the potential to increase understanding about the mechanisms underpinning health and disease phenotypes. In this study, we describe the most comprehensive analysis of common genetic variation on DNA methylation (DNAm) to date, using the Illumina EPIC array to profile samples from the UK Household...

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Literature Corpus work
ebc98bb9-b61d-560d-bed9-6d73275e4b1e
DOI
10.1101/297176
Open publication

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Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traitsDOI 10.1101/297176
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