Article

Integrative analysis of 10,000 epigenomic maps across 800 samples for regulatory genomics and disease dissection

2019-10-18

Abstract excerpt

To help elucidate genetic variants underlying complex traits, we develop EpiMap, a compendium of 833 reference epigenomes across 18 uniformly-processed and computationally-completed assays. We define chromatin states, high-resolution enhancers, activity patterns, enhancer modules, upstream regulators, and downstream target gene functions. We annotate 30,247 genetic variants associated with 534 traits, recognize pr...

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Literature Corpus work: 5dc5b61e-3cd3-57f8-8d50-68e17bb093af
DOI: 10.1101/810291

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