Article
Genetic-epigenetic interactions in cis: a major focus in the post-GWAS era.
Genome biology - 19 Jun 2017
Do Catherine, Shearer Alyssa, Suzuki Masako, Terry Mary Beth, Gelernter Joel, Greally John M, Tycko Benjamin
Abstract excerpt
Studies on genetic-epigenetic interactions, including the mapping of methylation quantitative trait loci (mQTLs) and haplotype-dependent allele-specific DNA methylation (hap-ASM), have become a major focus in the post-genome-wide-association-study (GWAS) era. Such maps can nominate regulatory sequence variants that underlie GWAS signals for common diseases, ranging from neuropsychiatric disorders to cancers....
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