Article

IFNγ regulates MR1 transcription and antigen presentation

2025-02-10

Abstract excerpt

Antigen presentation molecules play key roles in activating T cell immunity. Multiple complementary pathways are known to regulate classical MHC-I molecules at transcriptional, translational, and post-translational levels. Intracellular trafficking mechanisms dictating post-transcriptional regulation of MR1, the MHC Class I-like molecule which restricts MAIT cells, have been an area of focus; however, little is kn...

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Literature Corpus work: c5b0205a-a071-57fc-9b19-a6a97a2d3ad3
DOI: 10.1101/2025.02.09.637183

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