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Article

Interferon response factor-3 promotes the pro-Th2 activity of mouse lung CD11b+ conventional dendritic cells in response to house dust mite allergens.

European journal of immunology - 1 Nov 2016

Janss Thibaut, Mesnil Claire, Pirottin Dimitri, Lemaitre Pierre, Marichal Thomas, Bureau Fabrice, Desmet Christophe J

Abstract excerpt

Very few transcription factors have been identified that are required by antigen-presenting cells (APCs) to induce T helper type 2 (Th2) responses. Because lung CD11b+ conventional dendritic cells (CD11b+ cDCs) are responsible for priming Th2 responses in house-dust mite (HDM)-induced airway allergy, we used them as a model to identify transcriptional events regulating the pro-Th2 activity of cDCs. Transcriptomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27546168
DOI: 10.1002/eji.201646513

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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