Article

Investigating cardiomyopathies with atomistic simulations of cardiac Troponin

2019-01-01

Abstract excerpt

The heart can contract and relax at an increased rate during periods of intense physical activity or stress. Through a unique regulation mechanism, the orchestrator protein of muscle contraction, Troponin, is phosphorylated. The effects of post-translational modifications of this protein are physiologically well characterised; nevertheless, there is a lack of understanding at the molecular level. This delicate reg...

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Literature Corpus work: c5648a53-390e-5cda-9d05-b1bf19dc53ee
DOI: 10.25560/78681

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