Article

Integrative spatial and multi-omic profiling in bladder cancer links L1 retrotransposition to extrachromosomal DNA, genomic instability, and viral mimicry response

2025-08-02

Abstract excerpt

<h4>ABSTRACT</h4> Bladder cancer is one of the most frequent cancers and shows high recurrence rates. Despite recent advances, key knowledge gaps remain in understanding the molecular mechanisms of disease progression, which would support the development of early detection methods and effective personalized treatments. We apply integrated multi-omics and spatial analyses in a cohort of 49 bladder cancer patients...

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Literature Corpus work: 7e5b0d4a-7b36-5976-be8d-39c87c92c716
DOI: 10.1101/2025.07.30.667694

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