Article

An Expectation and Maximization Algorithm for Multivariate Genome-wide Association Studies (EMmvGWAS)

2025-12-05

Abstract excerpt

Genome-wide association studies (GWAS) commonly focus on one quantitative trait at a time, even when multiple traits are collected. However, joint analysis of multiple traits can increase the power to detect genetic associations by leveraging trait correlations. Multivariate GWAS is particularly important for identifying pleiotropic effects and uncovering shared genetic architecture underlying complex traits. Desp...

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Literature Corpus work: c362705d-040d-556a-a392-fdf0c6b8c311
DOI: 10.64898/2025.12.02.691906

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