Article

A scalable and robust variance components method reveals insights into the architecture of gene-environment interactions underlying complex traits

2023-12-13

Abstract excerpt

Understanding the contribution of gene-environment interactions (GxE) to complex trait variation can provide insights into mechanisms underlying disease risk, explain sources of heritability, and improve the accuracy of genetic risk prediction. While biobanks that collect genetic and deep phenotypic data over large numbers of individuals offer the promise of obtaining novel insights into GxE, our understanding of...

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Literature Corpus work: 88e9b381-364a-579f-9d0f-7e453af49689
DOI: 10.1101/2023.12.12.571316

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