Article
A rapid gene-based genome-wide association test with multivariate traits.
Human heredity - 1 Jan 2013
Basu Saonli, Zhang Yiwei, Ray Debashree, Miller Michael B, Iacono William G, McGue Matt
Abstract excerpt
OBJECTIVES: A gene-based genome-wide association study (GWAS) provides a powerful alternative to the traditional single single nucleotide polymorphism (SNP) association analysis due to its substantial reduction in the multiple testing burden and possible gain in power due to modeling multiple SNPs within a gene. A gene-based association analysis on multivariate traits is often of interest, but it imposes...
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