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Article

A general framework for association tests with multivariate traits in large-scale genomics studies.

Genetic epidemiology - 1 Dec 2013

He Qianchuan, Avery Christy L, Lin Dan-Yu

Abstract excerpt

Genetic association studies often collect data on multiple traits that are correlated. Discovery of genetic variants influencing multiple traits can lead to better understanding of the etiology of complex human diseases. Conventional univariate association tests may miss variants that have weak or moderate effects on individual traits. We propose several multivariate test statistics to complement univariate...

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PMID: 24227293
DOI: 10.1002/gepi.21759
PMCID: PMC3926135

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