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Article

Bayesian multivariate reanalysis of large genetic studies identifies many new associations

2019-05-16

Abstract excerpt

Genome-wide association studies (GWAS) have now been conducted for hundreds of phenotypes of relevance to human health. Many such GWAS involve multiple closely-related phenotypes collected on the same samples. However, the vast majority of these GWAS have been analyzed using simple univariate analyses, which consider one phenotype at a time. This is de-spite the fact that, at least in simulation experiments, multi...

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Literature Corpus work
798a9b0c-4711-58f1-9666-d0b5ac635d55
DOI
10.1101/638882
Open publication

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Bayesian multivariate reanalysis of large genetic studies identifies many new associationsDOI 10.1101/638882
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