Article
Accurate genetic and environmental covariance estimation with composite likelihood in genome-wide association studies.
PLoS genetics - 1 Jan 2021
Gao Boran, Yang Can, Liu Jin, Zhou Xiang
Abstract excerpt
Genetic and environmental covariances between pairs of complex traits are important quantitative measurements that characterize their shared genetic and environmental architectures. Accurate estimation of genetic and environmental covariances in genome-wide association studies (GWASs) can help us identify common genetic and environmental factors associated with both traits and facilitate the investigation of...
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