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Sulfatide Deficiency, An Early Alzheimer’s Lipidomic Signature, Causes Brain Ventricular Enlargement in the Absence of Classical Neuropathological Hallmarks

2022-09-20

Abstract excerpt

Alzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive memory loss and a decline in activities of daily life. Ventricular enlargement has been associated with worse performance on global cognitive tests and AD. Our previous studies demonstrated that brain sulfatides, myelin-enriched lipids, are dramatically reduced in subjects at the earliest clinically recognizable AD stages vi...

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Literature Corpus work
c3378de8-e908-573e-9202-67221ce2092f
DOI
10.20944/preprints202209.0290.v1
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Sulfatide Deficiency, An Early Alzheimer’s Lipidomic Signature, Causes Brain Ventricular Enlargement in the Absence of Classical Neuropathological HallmarksDOI 10.20944/preprints202209.0290.v1
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