Article

scGHOST: Identifying single-cell 3D genome subcompartments

2023-05-25

Abstract excerpt

New single-cell Hi-C (scHi-C) technologies enable probing of the genome-wide cell-to-cell variability in 3D genome organization from individual cells. Several computational methods have been developed to reveal single-cell 3D genome features based on scHi-C data, including A/B compartments, topologically-associating domains, and chromatin loops. However, no scHi-C analysis method currently exists for annotating si...

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Literature Corpus work: c22e7f2d-659a-56c2-950e-3df31ba0f1e4
DOI: 10.1101/2023.05.24.542032

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