Article

Revealing Hi-C subcompartments by imputing high-resolution inter-chromosomal chromatin interactions

2018-12-23

Abstract excerpt

The higher-order genome organization and its variation in different cellular conditions remains poorly understood. Recent high-resolution genome-wide mapping of chromatin interactions using Hi-C has revealed that chromosomes in the human genome are spatially segregated into distinct subcompartments. However, due to the requirement on sequencing coverage of the Hi-C data to define subcompartments, to date subcompar...

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Literature Corpus work: 3e65e947-1467-583d-b9a4-1a8a38c295bc
DOI: 10.1101/505503

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