Article

PLCG2 as a Risk Factor for Alzheimer's Disease

2020-06-08

Abstract excerpt

<title>Abstract</title> <p>Background Alzheimer's disease (AD) is characterized by robust microgliosis and phenotypic changes that accompany disease pathogenesis. Indeed, genetic variants in microglial genes are linked to risk for late-onset AD (LOAD). Phospholipase C 𝛾 2 (PLCG2) participates in the transduction of signals emanating from immune cell-surface receptors that regulate the inflammatory response and i...

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Literature Corpus work: c13f5ff2-299a-57dd-932a-e9999129692d
DOI: 10.21203/rs.3.rs-33082/v1

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