Article
PLCG2 as a Risk Factor for Alzheimer's Disease.
2020-06-30
Abstract excerpt
<h4>Background: </h4> Alzheimer's disease (AD) is characterized by robust microgliosis and phenotypic changes that accompany disease pathogenesis. Indeed, genetic variants in microglial genes are linked to risk for late-onset AD (LOAD). Phospholipase C š¾ 2 (PLCG2) participates in the transduction of signals emanating from immune cell-surface receptors that regulate the inflammatory response and is selectively exp...
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Identifiers and source
- Literature Corpus work
- 102a2750-5e5f-5d48-bb68-e54ff679408b
- DOI
- 10.21203/rs.3.rs-38216/v1
