Article

Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer

2024-08-26

Abstract excerpt

<h4>SUMMARY</h4> The immune composition of the tumor microenvironment (TME) has a major impact on the therapeutic response and clinical outcome in patients with colorectal cancer (CRC). Here, we comprehensively characterize the TME at the single-cell level by first building a large-scale atlas that integrates 4.27 million single cells from 1,670 patient samples. We then complemented the atlas with single-cell pro...

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Literature Corpus work: c0893fe6-45cf-58d2-b7de-fb486b21b563
DOI: 10.1101/2024.08.26.609563

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