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Article

Single‐cell analyses reveal suppressive tumor microenvironment of human colorectal cancer

1 Jun 2021

Abstract excerpt

Abstract Profiling heterologous cell types within tumors is essential to decipher tumor microenvironment that shapes tumor progress and determines the outcome of therapeutic response. Here, we comprehensively characterized transcriptomes of 34,037 single cells obtained from 12 treatment‐naïve patients with colorectal cancer. Our comprehensive evaluation revealed attenuated B‐cell antigen presentation, distinct...

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PMID: 34185431
DOI: 10.1002/ctm2.422

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