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Article

Characterization of immune cell populations in the tumor microenvironment of colorectal cancer using high definition spatial profiling

2024-06-05

Abstract excerpt

Colorectal cancer (CRC) is the second-deadliest cancer in the world, yet a deeper understanding of spatial patterns of gene expression in the tumor microenvironment (TME) remains elusive. Here, we introduce the Visium HD platform (10x Genomics) and use it to investigate human CRC and normal adjacent mucosal tissues from formalin fixed paraffin embedded (FFPE) samples. The first assay available on Visium HD is a pr...

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Literature Corpus work
a990cafe-47f6-59d6-b987-4fadc65afeaf
DOI
10.1101/2024.06.04.597233
Open publication

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Characterization of immune cell populations in the tumor microenvironment of colorectal cancer using high definition spatial profilingDOI 10.1101/2024.06.04.597233
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