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Article

Tumor-associated neutrophils: orchestrating cancer pathobiology and therapeutic resistance

3 Jul 2021

Abstract excerpt

Introduction: Neutrophils or polymorphonuclear cells (PMNs) account for a considerable portion of the tumor immune stroma. Emerging single-cell transcriptomic analyses have elucidated the striking cellular heterogeneity of PMNs during homeostasis and pathologic conditions and have established their diverse roles in cancer. PMNs have emerged as important players in cancer pathobiology and therapeutic resistance....

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PMID: 34236924
DOI: 10.1080/14728222.2021.1954162

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