Article

Constructing prognostic models for colorectal cancer through dynamic profiling of tumor-associated neutrophils via single-cell and bulk RNA sequencing

2024-02-29

Abstract excerpt

<h4>Background: </h4> This study elucidates tumor-associated neutrophils (TANs) role in the colorectal cancer (CRC) microenvironment and develops a predictive risk model. <h4>Methods: </h4>: Single-cell sequencing data from CRC patients in the Gene Expression Omnibus (GEO) database was utilized to identify subgroups of TANs and their marker genes. These subgroups' prognostic and diagnostic abilities were assessed...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e961243b-bd16-5526-b84e-76e65df8250d
DOI: 10.21203/rs.3.rs-3987118/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Constructing prognostic models for colorectal cancer through dynamic profiling of tumor-associated neutrophils via single-cell and bulk RNA sequencingDOI 10.21203/rs.3.rs-3987118/v1Read

Establishing and validating a prognostic model for colorectal cancer patients by integrating data from single-cell RNA sequencing and bulk RNA sequencingSemantic proximity Read

Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancerSemantic proximity Read

Single cell sequencing combined with transcriptome sequencing to build a prognostic model for colorectal cancerSemantic proximity Read

Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer.Semantic proximity Read

Construction and validation of neutrophil-related gene based risk models for assessing colon cancer prognosis and guiding immunotherapySemantic proximity Read

Integrated single-cell and bulk RNA-seq for constructing a prognostic risk model of immune-related genes in colorectal cancerSemantic proximity Read

A novel prognostic signature of immune‐related genes for patients with colorectal cancerSemantic proximity Read

Integrated singlecell and bulk RNA-seq analysis identifies a prognostic signature related to inflammation in colorectal cancerSemantic proximity Read

PANoptosis in deciphering immune characteristics and prognosis stratification of CRCSemantic proximity Read

Identification of a novel T cell-related signature to predict prognosis in colorectal cancer via integrating single-cell and bulk RNA sequencingSemantic proximity Read

Single-cell and WGCNA uncover a prognostic model and potential oncogenes in colorectal cancerSemantic proximity Read

A Comprehensive Multi-Omics Analysis Identifies a Robust Scoring System for Cancer-Associated Fibroblasts and Intervention Targets in Colorectal CancerSemantic proximity Read