Article

Single-Cell Analysis of Tumor-Specific Neutrophils During Gastric Cancer Progression Inspired a Hippo Targeted Antitumor Therapy

2021-05-27

Abstract excerpt

<title>Abstract</title> <p>Neutrophils are important for tumor immunosurveillance; yet their roles in tumorigenesis remain debating due to incomplete understanding of their heterogeneity and functional plasticity. Here we resolve at single-cell resolution the heterogeneity of neutrophils in tumor-bearing mice and patients with gastric cancer. Our results define CXCR2negCD44neg neutrophils as a tumor-specific (tsN...

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Literature Corpus work: ec7ae6be-2018-5005-80d5-a656a7e7ee4f
DOI: 10.21203/rs.3.rs-533205/v1

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