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Revisiting the immune microenvironment of human colorectal cancer in the era of single-cell and spatial omics

2025-08-25

Abstract excerpt

Colorectal cancer (CRC) remains a significant global health challenge, ranking among the leading causes of cancer-related morbidity and mortality. The tumor microenvironment (TME)—comprising immune cells, stromal elements, and extracellular matrix—plays a pivotal role in tumorigenesis, progression, and therapeutic resistance. Recent advancements in single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics...

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Literature Corpus work
553ce851-36d0-514a-9ff6-717d3b5eeef4
DOI
10.22541/au.175613488.82145372/v1
Open publication

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