Article

Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons

2021-09-12

Abstract excerpt

The maturation of neurons and the development of synapses – while emblematic of neurons – also rely on interactions with astrocytes and other glia. To study the role of glia-neuron interactions, we analyzed the transcriptomes of human pluripotent stem cell (hPSC)-derived neurons, from a total of 80 human donors, that were cultured with or without contact with glial cells. We found that the presence of astrocytes e...

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Literature Corpus work: c04a0eb2-df0a-5b29-a278-27207b2c5313
DOI: 10.1101/2021.09.11.459765

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