Article

<i>Mafb</i> Deficiency in Myeloid Cells Increases Susceptibility to <i>Mycobacterium tuberculosis</i> Infection in Mice

2025-07-10

Abstract excerpt

v-Maf avian musculoaponeurotic fibrosarcoma oncogene homolog B ( MAFB ) is a candidate gene associated with early tuberculosis onset identified by a genome-wide association study. Here, we investigated the role of Mafb in susceptibility to Mycobacterium tuberculosis ( Mtb ) infection in myeloid-specific Mafb -knockout ( Mafb -cKO) mice. We infected bone marrow-derived macrophages (BMMs) from Mafb -cKO mice...

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Literature Corpus work: c01a6abf-1a1e-5073-9ba2-275b09c40127
DOI: 10.1101/2025.07.06.663407

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