Article

Systems genetics uncover new loci containing functional gene candidates in <i>Mycobacterium tuberculosis</i> -infected Diversity Outbred mice

2023-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Mycobacterium tuberculosis, the bacillus that causes tuberculosis (TB), infects 2 billion people across the globe, and results in 8-9 million new TB cases and 1-1.5 million deaths each year. Most patients have no known genetic basis that predisposes them to disease. We investigated the complex genetic basis of pulmonary TB by modelling human genetic diversity with the Diversity Outbred mouse pop...

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Literature Corpus work: f76b2679-d47f-5b25-a44f-abd46a811e61
DOI: 10.1101/2023.12.21.572738

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